Publications · PhotoSynH2

2026

Nature Communications

A genetically encoded local learning rule enables physical learning in engineered bacteria

Satya Prakash, Clenira Varela, Mark Walsh, Roberto Galizi, Mark Isalan, Alfonso Jaramillo. Nat. Commun. https://doi.org/10.1038/s41467-026-78417-9 (2026).

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Journal of Biological Engineering

Engineering compact bacterial combinatorial promoters for two-input chemical AND switching

Satya Prakash, Alfonso Jaramillo. J. Biol. Eng. https://doi.org/10.1186/s13036-026-00728-8 (2026).

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Biochemistry

Probing the Role of Accessory FeS Clusters in Putative Sensory Group D [FeFe] Hydrogenase: Influence of the C-Terminal [4Fe-4S] Cluster on the Reactivity of TamHydS

Conrad Schumann, Maximilian Böhm, Prasenjit Bhowmik, Ping Huang, Princess R. Cabotaje, Henrik Land, Gustav Berggren. Biochemistry 65, 1280–1292 (2026).

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Marine Drugs

Synergistic Effects of Light and Salinity on Carotenoid and Biomass Composition of Synechocystis PCC6803 Cultures

Cecilia Faraloni, Gergely Erno Lakatos, Francesco Balestra, Anna Pugliese, Graziella Chini Zittelli, Bernardo Cicchi, Eleftherios Touloupakis, Giuseppe Torzillo. Mar. Drugs 24, 83 (2026).

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Frontiers in Marine Science

Growth and hydrogen production of the cyanobacterium Synechocystis sp. PCC 6803 in a marine salt medium

Gergely Ernő Lakatos, Bernardo Cicchi, Francesco Balestra, Anna Pugliese, Eleftherios Touloupakis, Graziella Chini Zittelli, Giuseppe Torzillo, Cecilia Faraloni. Front. Mar. Sci. 12, 1654421 (2026).

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2025

Analytical Chemistry

Reconsidering the Enzyme Kinetics of [FeFe]-Hydrogenases: Improved Turnover Rates and New Insights into pH and Potential Dependence with Eu(II)-Based Solution Assays

Eda Sönmez, Nikolaos Kostopoulos, Mira Gamache, Mun Hon Cheah, Ping Huang, Andrew J. Bagnall, Dawit T. Filmon, Ivan Voloshyn, Thomas Happe, Moritz Senger, Nicolas Plumeré, Alina Sekretareva, Gustav Berggren. Anal. Chem. 97, 26393–26403 (2025).

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Energies

Advances and Challenges in Biohydrogen Production by Photosynthetic Microorganisms

Cecilia Faraloni, Giuseppe Torzillo, Francesco Balestra, Isabela Calegari Moia, Raffaella Margherita Zampieri, Natalia Jiménez-Conejo, Eleftherios Touloupakis. Energies 18, 2319 (2025).

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Microbial Cell Factories

Structure-guided engineering of α-ketoisocaproate dioxygenase increases isobutene production in Synechocystis sp. PCC 6803

Conrad Schumann, Amit Kugler, Bhavik Ashwin Shah, Gustav Berggren, Henrik Land, Cecilia Blikstad, Karin Stensjö. Microb. Cell Fact. 24, 93 (2025).

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Physical Chemistry Chemical Physics

Indications for a universal hydrogen catalysis mechanism in [FeFe]-hydrogenases of different phylogenetic groups

Moritz Senger, Conrad Schumann, Princess R. Cabotaje, Afridi Zamader, Ping Huang, Henrik Land, Gustav Berggren. Phys. Chem. Chem. Phys. 27, 9864–9875 (2025).

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Energy & Fuels

Outlook on Synthetic Biology-Driven Hydrogen Production: Lessons from Algal Photosynthesis Applied to Cyanobacteria

Alfonso Jaramillo, Alessandro Satta, Filipe Pinto, Cecilia Faraloni, Graziella Chini Zittelli, Ana Margarita Silva Benavides, Giuseppe Torzillo, Conrad Schumann, Jorge Fernández Méndez, Gustav Berggren, Peter Lindblad, Maddalena Parente, Serena Esposito, Marcello Diano. Energy Fuels 39, 4987–5006 (2025).

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Journal of the American Chemical Society

Probing the Influence of the Protein Scaffold on H-Cluster Reactivity via Gain-of-Function Studies─Improved H2 Evolution and O2 Tolerance through Rational Design of [FeFe] Hydrogenase

Princess R. Cabotaje, Alina Sekretareva, Moritz Senger, Ping Huang, Kaija Walter, Holly J. Redman, Nicholas Croy, Sven T. Stripp, Henrik Land, Gustav Berggren. J. Am. Chem. Soc. 147, 4654–4666 (2025).

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2024

Microorganisms

Dark Anaerobic Conditions Induce a Fast Induction of the Xanthophyll Cycle in Chlamydomonas reinhardtii When Exposed to High Light

Cecilia Faraloni, Eleftherios Touloupakis, Giuseppe Torzillo. Microorganisms 12, 2264 (2024).

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Scientific Reports

T7 phage-assisted evolution of riboswitches using error-prone replication and dual selection

Eduardo Goicoechea Serrano, Carlos Blázquez-Bondia, Alfonso Jaramillo. Sci. Rep. 14, 2377 (2024).

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Journal of the American Chemical Society

Kinetic Modeling of the Reversible or Irreversible Electrochemical Responses of FeFe-Hydrogenases

Andrea Fasano, Carole Baffert, Conrad Schumann, Gustav Berggren, James A. Birrell, Vincent Fourmond, Christophe Léger. J. Am. Chem. Soc. 146, 1455–1466 (2024).

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2023

Applied Microbiology and Biotechnology

Solar bioreactors used for the industrial production of microalgae

Jiří Masojídek, Richard Lhotský, Karolína Štěrbová, Graziella Chini Zittelli, Giuseppe Torzillo. Appl. Microbiol. Biotechnol. 107, 6439–6458 (2023).

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Frontiers in Microbiology

Novel concepts and engineering strategies for heterologous expression of efficient hydrogenases in photosynthetic microorganisms

Conrad Schumann, Jorge Fernández Méndez, Gustav Berggren, Peter Lindblad. Front. Microbiol. 14, 1179607 (2023).

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BioDesign Research

qSanger: Quantification of Genetic Variants in Bacterial Cultures by Sanger Sequencing

Satya Prakash, Adrian Racovita, Teresa Petrucci, Roberto Galizi, Alfonso Jaramillo. Biodes. Res. 5, 0007 (2023).

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